Juxtapapillary diverticulum

Duodenal diverticula may cause difficulties with cannulation as the papilla may be located on the edge or rarely inside a diverticulum. Note relationship of papilla to duodenal diverticula.

Periampullary diverticula and sphincterotomy Diverticula do not increase the risk of sphincterotomy unless the papilla is located on the edge or inside a large diverticulum.
Cannulation may be technically more difficult and the risk of perforation is increased as a result of a deviated cut.